L-Tryptophan

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

一种必需氨基酸，是婴儿正常生长和成人氮平衡所必需的。

An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

Cell Viability Assay Cell Line:pTr2 cell Concentration:500, 1000 μM Incubation Time:48 h Result:500 and 1000 μM groups had decreased cell viability by 7% and 22%, respectively, at 48 h posttreatment.Cell Cycle Analysis Cell Line:pTr2 cell Concentration:500, 1000 μM Incubation Time:48 h Result:The percentage of pTr2 cells in the G1 phase increased from 65.70% (control) to 71.37% (500 mM) and 73.86% (1000 mM).Cell Migration Assay Cell Line:hBMSCs Concentration:10 μM Incubation Time:For three weeks Result:Exhibited a higher ability for migration than the control group.RT-PCR Cell Line:hBMSCs Concentration:10 μM Incubation Time:For three weeks Result:Decreased mRNA levels of adipogenic markers PPARγ and LPL.

Animal Model:Five-week-old C57BL/6 miceDosage:10, 50 kg/mg Administration:Intraperitoneally; daily; for consecutive three weeks Result:The concentration of 50 mg/kg/day induced a significant increase in the number of SSEA-4 positive cells. Increased the mRNA levels of Nanog and Oct-4 and the colony-forming ability of mBMSCs with 50 mg/kg/day.

Tryptophan | NSC 13119 | NSC-13119 | NSC13119 | Ardeytropin | L-Tryptophane

Immunology/Inflammation

Amino Acids and Derivatives

Amino Acids and Derivatives

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73-22-3

204.23

C11H12N2O2

>98% (HPLC)

soluble in Water

O=C(O)C(N)CC1=CNC2=C1C=CC=C2

tryptophan

(-20℃)

With Ice Pack

≥ 2 years