
L-Propargylglycine
CAS No. 23235-01-0
L-Propargylglycine ( (S)-Propargylglycine,(S)-alpha.Propargylglycine,Propargylglycine )
产品货号. M22868 CAS No. 23235-01-0
L-Propargylglycine 是酶的抑制剂。L-Propargylglycine (LPG) 以剂量和时间依赖性方式不可逆地抑制 Crotalus adamanteus 和 Crotalus atrox 的酶。失活是不可逆的,受到底物l-苯丙氨酸的显着保护。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
100MG | ¥316 | 有现货 |
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500MG | ¥794 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称L-Propargylglycine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述L-Propargylglycine 是酶的抑制剂。L-Propargylglycine (LPG) 以剂量和时间依赖性方式不可逆地抑制 Crotalus adamanteus 和 Crotalus atrox 的酶。失活是不可逆的,受到底物l-苯丙氨酸的显着保护。
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产品描述L-Propargylglycine is an inhibitor of the enzyme.l-propargylglycine (LPG) irreversibly inhibited the enzyme from Crotalus adamanteus and Crotalus atrox in a dose- and time-dependent manner.?Inactivation was irreversible which was significantly protected by the substrate l-phenylalanine.?A Kitz-Wilson replot of the inhibition kinetics suggested formation of reversible enzyme-LPG complex, which occurred prior to modification and inactivation of the enzyme.?UV-visible and fluorescence spectra of the enzyme and the cofactor strongly suggested formation of covalent adduct between LPG and an active site residue of the enzyme.?A molecular modeling study revealed that the FAD-binding, substrate-binding and the helical domains are conserved in SV-LAAOs and both His223 and Arg322 are the important active site residues that are likely to get modified by LPG.
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体外实验——
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体内实验——
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同义词(S)-Propargylglycine,(S)-alpha.Propargylglycine,Propargylglycine
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number23235-01-0
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分子量113.11
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分子式C5H7NO2
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纯度>98% (HPLC)
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溶解度DMSO:Soluble
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SMILESC#CCC(C(=O)O)N
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Irreversible inactivation of snake venom l-amino acid oxidase by covalent modification during catalysis of l-propargylglycine
产品手册




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