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L-Kynurenine

CAS No. 2922-83-0

L-Kynurenine ( (S)-Kynurenine )

产品货号. M19725 CAS No. 2922-83-0

L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥340 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    L-Kynurenine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
  • 产品描述
    L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
  • 同义词
    (S)-Kynurenine
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    Endogenous Metabolite
  • 受体
    Human Endogenous Metabolite;AhR
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2922-83-0
  • 分子量
    208.21
  • 分子式
    C10H12N2O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:50 mg/mL (240.14 mM) Need ultrasonic;Water:4mg/mL(at 20°C);0.5M HCL:50mg/mL
  • SMILES
    N[C@@H](CC(=O)c1ccccc1N)C(O)=O
  • 化学全称
    (S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Kolho K L Pessia A Jaakkola T et al. Faecal and serum metabolomics in paediatric inflammatory bowel disease[J]. Journal of Crohns & Colitis 2017 11(3):321-334.
产品手册
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