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首页- Products - Others - Other Targets - L-BUTHIONINE-(SR)-SULFOXIMINE

L-BUTHIONINE-(SR)-SULFOXIMINE

CAS No. 83730-53-4

L-BUTHIONINE-(SR)-SULFOXIMINE ( L-Butionine sulfoximine )

产品货号. M20128 CAS No. 83730-53-4

L-Buthionine-(SR)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥381 有现货
100MG ¥648 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    L-BUTHIONINE-(SR)-SULFOXIMINE
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    L-Buthionine-(SR)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.
  • 产品描述
    L-Buthionine-(SR)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.
  • 同义词
    L-Butionine sulfoximine
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    γ-glutamylcysteine synthetase
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    83730-53-4
  • 分子量
    222.31
  • 分子式
    C8H18N2O3S
  • 纯度
    >98% (HPLC)
  • 溶解度
    H2O:41.67 mg/mL (187.44 mM; Need ultrasonic)
  • SMILES
    CCCCS(=N)(=O)CC[C@H](N)C(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Fruehauf JP et al. Selective and synergistic activity of L-SR-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase. Pigment Cell Res. 1997 Aug;10(4):236-49.
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