
Kinetin
CAS No. 525-79-1
Kinetin ( N6-furfuryladenine | NSC 23119 )
产品货号. M14860 CAS No. 525-79-1
激动素是细胞分裂素的一种,是一类促进细胞分裂的植物激素。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
200MG | ¥235 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Kinetin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述激动素是细胞分裂素的一种,是一类促进细胞分裂的植物激素。
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产品描述Kinetin is a type of cytokinin, a class of plant hormone that promotes cell division.(In Vitro):Kinetin (N6-furfuryladenine) shows to have a direct effect on superoxide dismutase activity in plants; prevent oxidation of unsaturated acids in plant membranes; slow down development and aging in insects, by reducing their fecundity and increasing the specific activity of catalase; and delay the onset of many age-related characteristics that appear in normal human skin fibroblasts undergoing aging in vitro. Kinetin (70-150 μM) markedly suppressed hydroxyl radical formation by about 41% and 76%, respectively.The plant cytokinin kinetin dramatically increases exon 20 inclusion in RNA isolated from cultured familial dysautonomia (FD) cells.(In Vivo):Kinetin (N6-furfuryladenine) (2-6 mg/kg; injection into the tail vein) effectively prevents ADP-induced acute pulmonary thrombosis in mice.Subjects received 23.5 mg/kg/d for 28 d. An increase in WT IKBKAP mRNA expression in leukocytes was noted after 8 d in six of eight individuals; after 28 d, the mean increase compared with baseline was significant.
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体外实验Kinetin (N6-furfuryladenine) shows to have a direct effect on superoxide dismutase activity in plants; prevent oxidation of unsaturated acids in plant membranes; slow down development and aging in insects, by reducing their fecundity and increasing the specific activity of catalase; and delay the onset of many age-related characteristics that appear in normal human skin fibroblasts undergoing aging in vitro. Kinetin (70-150 μM) markedly suppressed hydroxyl radical formation by about 41% and 76%, respectively. The plant cytokinin kinetin dramatically increases exon 20 inclusion in RNA isolated from cultured familial dysautonomia (FD) cells.
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体内实验Kinetin (N6-furfuryladenine) (2-6 mg/kg; injection into the tail vein) effectively prevents ADP-induced acute pulmonary thrombosis in mice.Subjects received 23.5 mg/kg/d for 28 d. An increase in WT IKBKAP mRNA expression in leukocytes was noted after 8 d in six of eight individuals; after 28 d, the mean increase compared with baseline was significant. Animal Model:ADP-induced acute pulmonary thrombosis 20-24 g mice (ICR strain) Dosage:2, 4, 6 mg/kg Administration:Injection into the tail vein Result:Reduced mortality to 70%, 40% and 35% at 2, 4, and 6 mg/kg, respectively.
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同义词N6-furfuryladenine | NSC 23119
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通路Others
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靶点Other Targets
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受体Others
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研究领域Other Indications
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适应症——
化学信息
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CAS Number525-79-1
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分子量215.21
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分子式C10H9N5O
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纯度>98% (HPLC)
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溶解度DMSO: 8 mg/mL warmed (37.17 mM)
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SMILES9H-Purin-6-amine, N-(2-furanylmethyl)-
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化学全称9H-Purin-6-amine, N-(2-furanylmethyl)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Chiu PC, et al. J Cosmet Dermatol, 2007, 6(4), 243-249.