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Kinetin

CAS No. 525-79-1

Kinetin ( N6-furfuryladenine | NSC 23119 )

产品货号. M14860 CAS No. 525-79-1

激动素是细胞分裂素的一种,是一类促进细胞分裂的植物激素。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
200MG ¥235 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Kinetin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    激动素是细胞分裂素的一种,是一类促进细胞分裂的植物激素。
  • 产品描述
    Kinetin is a type of cytokinin, a class of plant hormone that promotes cell division.(In Vitro):Kinetin (N6-furfuryladenine) shows to have a direct effect on superoxide dismutase activity in plants; prevent oxidation of unsaturated acids in plant membranes; slow down development and aging in insects, by reducing their fecundity and increasing the specific activity of catalase; and delay the onset of many age-related characteristics that appear in normal human skin fibroblasts undergoing aging in vitro. Kinetin (70-150 μM) markedly suppressed hydroxyl radical formation by about 41% and 76%, respectively.The plant cytokinin kinetin dramatically increases exon 20 inclusion in RNA isolated from cultured familial dysautonomia (FD) cells.(In Vivo):Kinetin (N6-furfuryladenine) (2-6 mg/kg; injection into the tail vein) effectively prevents ADP-induced acute pulmonary thrombosis in mice.Subjects received 23.5 mg/kg/d for 28 d. An increase in WT IKBKAP mRNA expression in leukocytes was noted after 8 d in six of eight individuals; after 28 d, the mean increase compared with baseline was significant.
  • 体外实验
    Kinetin (N6-furfuryladenine) shows to have a direct effect on superoxide dismutase activity in plants; prevent oxidation of unsaturated acids in plant membranes; slow down development and aging in insects, by reducing their fecundity and increasing the specific activity of catalase; and delay the onset of many age-related characteristics that appear in normal human skin fibroblasts undergoing aging in vitro. Kinetin (70-150 μM) markedly suppressed hydroxyl radical formation by about 41% and 76%, respectively. The plant cytokinin kinetin dramatically increases exon 20 inclusion in RNA isolated from cultured familial dysautonomia (FD) cells.
  • 体内实验
    Kinetin (N6-furfuryladenine) (2-6 mg/kg; injection into the tail vein) effectively prevents ADP-induced acute pulmonary thrombosis in mice.Subjects received 23.5 mg/kg/d for 28 d. An increase in WT IKBKAP mRNA expression in leukocytes was noted after 8 d in six of eight individuals; after 28 d, the mean increase compared with baseline was significant. Animal Model:ADP-induced acute pulmonary thrombosis 20-24 g mice (ICR strain) Dosage:2, 4, 6 mg/kg Administration:Injection into the tail vein Result:Reduced mortality to 70%, 40% and 35% at 2, 4, and 6 mg/kg, respectively.
  • 同义词
    N6-furfuryladenine | NSC 23119
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Other Indications
  • 适应症
    ——

化学信息

  • CAS Number
    525-79-1
  • 分子量
    215.21
  • 分子式
    C10H9N5O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 8 mg/mL warmed (37.17 mM)
  • SMILES
    9H-Purin-6-amine, N-(2-furanylmethyl)-
  • 化学全称
    9H-Purin-6-amine, N-(2-furanylmethyl)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Chiu PC, et al. J Cosmet Dermatol, 2007, 6(4), 243-249.
产品手册
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