Kinetensin

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Kinetensin is a neurotensin-like peptide.

Kinetensin is a neurotensin-like peptide.(In Vitro):The peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium.(In Vivo):Kinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats.

Kinetensin (human)

Others

Other Targets

Neurotensin Receptor

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103131-69-7

1172.4

C56H85N17O11

>98% (HPLC)

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Sequence:Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu

(-20℃)

With Ice Pack

≥ 2 years