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KF38789

CAS No. 257292-29-8

KF38789 ( KF 38789 )

产品货号. M27643 CAS No. 257292-29-8

KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥996 有现货
10MG ¥1596 有现货
25MG ¥3046 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    KF38789
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.
  • 产品描述
    KF 38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.(In Vitro):KF 38789, inhibited the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 microM. Cell adhesion to both E-selectin-Ig and L-selectin-Ig were not affected even by 100 microM of KF 38789. Moreover, KF 38789 inhibited P-selectin-induced superoxide production from human polymorphonuclear cells. Intravenously injected KF 38789 significantly inhibited the TG-induced accumulation of leukocytes in the mouse peritoneal cavity (p<0.01).(In Vivo):KF 38789 significantly reduced mechanical allodynia in the facial carrageenan-injected mice.
  • 同义词
    KF 38789
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    fatty acid 3 receptor (FA3R)
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    257292-29-8
  • 分子量
    375.4
  • 分子式
    C19H21NO5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    COc1ccc(C2CC(=NCCS2)c2c(O)cc(C)oc2=O)c(OC)c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Getachew B, et al. Butyrate Protects Against Salsolinol-Induced Toxicity in SH-SY5Y Cells: Implication for Parkinson's Disease. Neurotox Res. 2020 Oct;38(3):596-602.
产品手册
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