JNK-IN-7 ( JNK-IN-7; JNK inhibitor;JNKIN7; JNK IN 7 )

产品货号. M17280 CAS No. 1408064-71-0

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

JNK-IN-7
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

JNK-IN-7 is a selective JNK1/2/3 inhibitor (IC50: 1.54/1.99/0.75 nM). It can also inhibit phosphorylation of c-Jun, which is a substrate of JNK kinase.
产品描述

JNK-IN-7 is a relatively selective JNKs inhibitor(IC50= 1.54/1.99/0.75 for JNK1/2/3); also bound to IRAK1, PIK3C3, PIP5K3 and PIP4K2C.
同义词

JNK-IN-7; JNK inhibitor;JNKIN7; JNK IN 7
通路

Others
靶点

Other Targets
受体

JNK1; JNK2; JNK3
研究领域

Inflammation/Immunology
适应症

——

CAS Number

1408064-71-0
分子量

493.56
分子式

C28H27N7O2
纯度

98%
溶解度

DMSO : 33.33 mg/mL. 67.53 mM; H2O : < 0.1 mg/mL
SMILES

C(=O)(Nc1cccc(c1)C(=O)Nc1ccc(cc1)Nc1nccc(n1)c1cnccc1)/C=C/CN(C)C
化学全称

3-[[(E)-4-(Dimethylamino)but-2-enoyl]amino]-N-[4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide

1. Zhang T, et al. Chem Biol, 2012, 19(1): 140-154.

计算器

产品手册

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