021-51111890
购物车（）
sales@molnova.cn
JNJ-26489112
CAS No. 871824-55-4
JNJ-26489112 ( JNJ26489112 )
产品货号. M16338 CAS No. 871824-55-4
JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
|
| 50MG | ￥16038 | 有现货 |
|
| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称JNJ-26489112
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures.
-
产品描述JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures; exhibits very weak inhibition of human CA-II (IC50=35 μM); inhibits Na+, kainate, and KCNQ2 channels to varying degrees, while moderately potentiating GABA current and inhibiting N-methyl-D-aspartic acid current, its action at several targets appears to be responsible for the observed neurostabilizing effects; shows limited seizure spread and elevated seizure threshold in preclinical animal models.Epilepsy Discontinued
-
同义词JNJ26489112
-
通路Others
-
靶点Other Targets
-
受体Other Targets
-
研究领域Neurological Disease
-
适应症Epilepsy
化学信息
-
CAS Number871824-55-4
-
分子量278.71
-
分子式C9H11ClN2O4S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESO=S(NC[C@@H]1OC2=CC=C(Cl)C=C2OC1)(N)=O
-
化学全称(S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. McComsey DF, et al. J Med Chem. 2013 Nov 27;56(22):9019-30.
产品手册
关联产品
-
2-Glucosyloxy-4-meth...
Z-GMCA is a useful organic compound for research related to life sciences.
-
Talatisamine
Talatisamine (12 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ4 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response.
-
2-Aminoethylphosphon...
Ciliatine belongs to the class of organic compounds known as organic phosphonic acids. Ciliatine has been primarily detected in urine.
