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JNJ-26489112
CAS No. 871824-55-4
JNJ-26489112 ( JNJ26489112 )
产品货号. M16338 CAS No. 871824-55-4
JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
|
| 50MG | ￥16038 | 有现货 |
|
| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称JNJ-26489112
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures.
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产品描述JNJ-26489112 (JNJ26489112) is a broad-spectrum anticonvulsant that displays activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures; exhibits very weak inhibition of human CA-II (IC50=35 μM); inhibits Na+, kainate, and KCNQ2 channels to varying degrees, while moderately potentiating GABA current and inhibiting N-methyl-D-aspartic acid current, its action at several targets appears to be responsible for the observed neurostabilizing effects; shows limited seizure spread and elevated seizure threshold in preclinical animal models.Epilepsy Discontinued
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同义词JNJ26489112
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Neurological Disease
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适应症Epilepsy
化学信息
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CAS Number871824-55-4
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分子量278.71
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分子式C9H11ClN2O4S
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纯度>98% (HPLC)
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溶解度——
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SMILESO=S(NC[C@@H]1OC2=CC=C(Cl)C=C2OC1)(N)=O
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化学全称(S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. McComsey DF, et al. J Med Chem. 2013 Nov 27;56(22):9019-30.
产品手册
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