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JKE-1674
CAS No. 2421119-60-8
JKE-1674 ( —— )
产品货号. M28123 CAS No. 2421119-60-8
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥915 | 有现货 |
|
| 10MG | ￥1482 | 有现货 |
|
| 25MG | ￥3013 | 有现货 |
|
| 50MG | ￥4836 | 有现货 |
|
| 100MG | ￥7736 | 有现货 |
|
| 200MG | ￥10368 | 有现货 |
|
| 500MG | ￥15309 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称JKE-1674
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210.
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产品描述JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210.(In Vitro):JKE-1674 reduces the viability of LOX-IMVI cancer cells with an EC50 of 0.03 μM and in a panel of additional cancer cell lines. JKE-1674 is completely rescued by ferroptosis inhibitors.(In Vivo):JKE-1674 (50?mg/kg; p.o.) could be detected in the serum of mice dosed orally with the compound.
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同义词——
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通路Others
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靶点Other Targets
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受体IL-5
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研究领域——
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适应症——
化学信息
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CAS Number2421119-60-8
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分子量451.3
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分子式C20H20Cl2N4O4
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C(C(C[N+]([O-])=O)=NO)N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)CC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ian D Pavord, From DREAM to REALITI-A and beyond: Mepolizumab for the treatment of eosinophil-driven diseases. Allergy. 2022 Mar;77(3):778-797.
产品手册
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