021-51111890
购物车（）
sales@molnova.cn
JKE-1674
CAS No. 2421119-60-8
JKE-1674 ( —— )
产品货号. M28123 CAS No. 2421119-60-8
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥915 | 有现货 |
|
| 10MG | ￥1482 | 有现货 |
|
| 25MG | ￥3013 | 有现货 |
|
| 50MG | ￥4836 | 有现货 |
|
| 100MG | ￥7736 | 有现货 |
|
| 200MG | ￥10368 | 有现货 |
|
| 500MG | ￥15309 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称JKE-1674
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210.
-
产品描述JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210.(In Vitro):JKE-1674 reduces the viability of LOX-IMVI cancer cells with an EC50 of 0.03 μM and in a panel of additional cancer cell lines. JKE-1674 is completely rescued by ferroptosis inhibitors.(In Vivo):JKE-1674 (50?mg/kg; p.o.) could be detected in the serum of mice dosed orally with the compound.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体IL-5
-
研究领域——
-
适应症——
化学信息
-
CAS Number2421119-60-8
-
分子量451.3
-
分子式C20H20Cl2N4O4
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESO=C(C(C[N+]([O-])=O)=NO)N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=C(Cl)C=C3)CC1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Ian D Pavord, From DREAM to REALITI-A and beyond: Mepolizumab for the treatment of eosinophil-driven diseases. Allergy. 2022 Mar;77(3):778-797.
产品手册
关联产品
-
p-Ethoxybenzoic acid
4-Ethoxybenzoic acid is a compound of luminescent bioapplication.
-
3-Hydroxybenzaldehyd...
3-Hydroxybenzaldehyde is a compound useful in organic synthesis.
-
2-ATHBI
2-ATHBI is a S1P lyase inhibitor.
