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JK-P3
CAS No. 942655-44-9
JK-P3 ( 3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide )
产品货号. M17680 CAS No. 942655-44-9
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥446 | 有现货 |
|
| 10MG | ￥794 | 有现货 |
|
| 25MG | ￥1798 | 有现货 |
|
| 50MG | ￥3216 | 有现货 |
|
| 100MG | ￥4771 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称JK-P3
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
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产品描述JK-P3 is novel inhibitor of VEGFR-2. JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50 = 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.
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同义词3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide
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通路Others
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靶点Other Targets
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受体VEGFR2
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研究领域——
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适应症——
化学信息
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CAS Number942655-44-9
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分子量323.35
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分子式C18H17N3O3
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纯度98%
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溶解度——
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SMILESCOc1c(cc(cc1)C(=O)Nc1n[nH]c(c1)c1ccccc1)OC
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化学全称3,4-Dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)-benzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Antony M. Latham, et al. Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation. VEGF Signaling pp 121-131
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