JC-1
CAS No. 3520-43-2
JC-1 ( CBIC2 )
产品货号. M22703 CAS No. 3520-43-2
JC-1 is a fluorescent lipophilic carbocyanine dye. It has been used to measure mitochondrial membrane potential.?JC 1 can be used in a probe for measuring mitochondrial membrane potential by flow cytometry. JC-1 fluorescence is usually excited by the 488?nm laser wavelength common in flow cytometers. JC-1 (2.5?μM) exposed to murine L1210 lymphoblasts, can be detected the presence of both cytoplasmic JC-1 monomer and mitochondrial J-aggregates in these cells.
纯度: >98% (HPLC)
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥656 | 有现货 |
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5MG | ¥1239 | 有现货 |
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10MG | ¥2041 | 有现货 |
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25MG | ¥3426 | 有现货 |
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50MG | ¥5087 | 有现货 |
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100MG | ¥7233 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
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生物学信息
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产品名称JC-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述JC-1 is a fluorescent lipophilic carbocyanine dye. It has been used to measure mitochondrial membrane potential.?JC 1 can be used in a probe for measuring mitochondrial membrane potential by flow cytometry. JC-1 fluorescence is usually excited by the 488?nm laser wavelength common in flow cytometers. JC-1 (2.5?μM) exposed to murine L1210 lymphoblasts, can be detected the presence of both cytoplasmic JC-1 monomer and mitochondrial J-aggregates in these cells.
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产品描述JC-1 is a fluorescent lipophilic carbocyanine dye. It has been used to measure mitochondrial membrane potential.?JC 1 can be used in a probe for measuring mitochondrial membrane potential by flow cytometry. JC-1 fluorescence is usually excited by the 488?nm laser wavelength common in flow cytometers. JC-1 (2.5?μM) exposed to murine L1210 lymphoblasts, can be detected the presence of both cytoplasmic JC-1 monomer and mitochondrial J-aggregates in these cells. Fluorescent labeling of mitochondria with either JC-1 (1 μg/mL, 15 min), reveals that are distributed irregularly, resulting in regions of high and low mitochondrial content within astrocytes. JC-1 is avidly accumulated in sensitive K562 cells where it displays both a green cytoplasmic and red mitochondrial fluorescence. JC-1 is poorly accumulated in resistant K562 cells, which displays only a slight green fluorescence. JC-1 has been shown to interact with α-synuclein at the acidic C-terminal region with a Kd of 2.6 μM. JC-1 itself does not accelerate the protein aggregation of α-synuclein in the absence of iron, insted, it decelerates the aggregation process by extending the lag phase approx.
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同义词CBIC2
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number3520-43-2
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分子量652.23
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分子式C25H27Cl4IN4
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纯度>98% (HPLC)
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溶解度DMSO:14 mg/mL(21.46 mM)
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SMILES[I-].CCN1\C(=C/C=C/c2n(CC)c3cc(Cl)c(Cl)cc3[n+]2CC)N(CC)c2cc(Cl)c(Cl)cc12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Hyoscyamine Sulfate is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity.
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Emoxipine
Emoxipine is an antidepressant agent.The influence of emoxipine (2-ethyl-6-methyl-3-hydroxypyridine hydrochloride) and mexidol (2-ethyl-6-methyl-3-hydroxypyridine succinate) on the content of lipid peroxidation products in peripheral blood and the dynamics of clinical symptoms of gastrointestinal tract pathology has been studied in patients of middle and senile age with atherosclerosis in the abdominal aorta.
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Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.