J8-C8
CAS No. 1150565-77-7
J8-C8 ( acyl-HSLs inhibitor J8-C8 )
产品货号. M10530 CAS No. 1150565-77-7
J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称J8-C8
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
-
产品描述J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production; inhibits C8-HSL synthesis in a dose-dependent manner; a new class of quorum sensing (QS)-inhibiting therapeutic agents.
-
同义词acyl-HSLs inhibitor J8-C8
-
通路GPCR/G Protein
-
靶点Antibacterial
-
受体Antibacterial
-
研究领域——
-
适应症——
化学信息
-
CAS Number1150565-77-7
-
分子量237.34
-
分子式C14H23NO2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称N-(3-oxocyclohex-1-en-1-yl)octanamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Chung J, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12089-94.
产品手册
关联产品
-
Pachybasin
Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively.
-
Mecillinam
Mecillinam, an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2).
-
MAC13772
MAC13772 is a potent inhibitor of BioA with an IC50 of 250 nM, a novel antibacterial inhibitor that selectively inhibits PABA biosynthesis in M tuberculosis.