021-51111890
购物车（0）
sales@molnova.cn
J-104871
CAS No. 191088-19-4
J-104871 ( —— )
产品货号. M33992 CAS No. 191088-19-4
J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥2519 | 有现货 |
|
| 5MG | ￥3900 | 有现货 |
|
| 10MG | ￥5588 | 有现货 |
|
| 25MG | ￥8446 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称J-104871
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
-
产品描述J-104871 (UNII-6137X5QNJF) is a novel farnesyltransferase (FTase) inhibitor that competitively blocks Ras farnesylation in vivo, inhibits Ras processing in activated H-ras-transformed NIH3T3 cells, and suppresses tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.
-
体外实验——
-
体内实验——
-
同义词——
-
通路MAPK/ERK Signaling
-
靶点Ras
-
受体Ras
-
研究领域——
-
适应症——
化学信息
-
CAS Number191088-19-4
-
分子量708.67
-
分子式C38H32N2O12
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESC(O)(=O)C1(C(O)=O)O[C@H](C(N([C@@H]([C@H](C/C=C/C2=NC=3C(O2)=CC=CC3)C=4C=C5C(=CC4)OCO5)C)CC6=CC7=C(C=C6)C=CC=C7)=O)[C@H](C(O)=O)O1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册
关联产品
-
ADT-007
ADT-007 is an orally active and selective pan-RAS inhibitor with potent anticancer activity.ADT-007 blocks GTP activation of RAS and MAPK/AKT signaling by binding to anucleotide RAS.ADT-007 is used in the study of gastrointestinal cancers.
-
SCH 54292
SCH 54292 是一种有效的 Ras-GEF 相互作用抑制剂，IC50 为 0.7 uM。
-
KRAS inhibitor 11
KRAS 抑制剂 11 是一种一流的、高亲和力、非共价变构 KRAS 抑制剂。
