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Isoimperatorin

CAS No. 482-45-1

Isoimperatorin ( Iso-imperatorin )

产品货号. M18621 CAS No. 482-45-1

Isoimperatorin 是一种抗炎剂,对乙酰胆碱酯酶 (AChE) 有显着的抑制作用。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥332 有现货
50MG ¥535 有现货
100MG ¥786 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Isoimperatorin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Isoimperatorin 是一种抗炎剂,对乙酰胆碱酯酶 (AChE) 有显着的抑制作用。
  • 产品描述
    Isoimperatorin is a COX-2 inhibitor. It induces cell cycle arrest and inhibits proliferation in melanoma cells, prevents activation of carcinogens, increases expression of PPAR-γ, and suppresses degranulation of bone marrow-derived mast cells.
  • 体外实验
    During a screening program for new agrochemicals from Chinese medicinal herbs, the ethanol extract of Notopterygium incisum rhizomes is found to possess strong nematicidal activity against the two species of nematodes, Bursaphelenchus xylophilus and Meloidogyne incognita. Based on bioactivity-guided fractionation, the four constituents are isolated from the ethanol extract and identified as Columbianetin, Falcarindiol, Falcarinol, and Isoimperatorin. Isoimperatorin also has LC50 values of 21.83 μg/mL against B. xylophilus. When using 15 min UV light treatment, falcarindiol, falcarinol, and isoimperatorin demonstrated almost five times more toxic to the southern root-knot nematodes than in dark treatment while columbianetin showed only two times more toxic. isoimperatorin has been demonstrated to possess insecticidal activity against several insects, such as the cabbage aphid (Brevicoryne brassicae). Isoimperatorin is identified in the active fraction of Angelica dahurica (AD) extract. Isoimperatorin is usually used as the internal standard (IS).
  • 体内实验
    ——
  • 同义词
    Iso-imperatorin
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    AChE
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    482-45-1
  • 分子量
    270.28
  • 分子式
    C16H14O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?Ethanol : 8.33 mg/mL (30.82 m)
  • SMILES
    CC(=CCOc1c2ccc(=O)oc2cc2c1cco2)C
  • 化学全称
    4-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Chen TL, et al. Fitoterapia. 2014 Mar;93:88-97.
产品手册
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