Isobutylshikonin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

异丁基紫草素具有明显的抗氧化活性，对ABTS+有很好的自由基清除活性，但对DPPH·有中等的抑制作用。

Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·.(In Vitro):Five red shikonin pigments, deoxyshikonin, shikonin, acetylshikonin, Isobutylshikonin, and beta-hydroxyisovalerylshikonin, were isolated from the roots of Lithospermum erythrorhizon cultivated in Korea. The purified pigments were red, purple, and blue at acidic, neutral, and alkaline pH values, respectively. Physical stability of the purified pigments against heat and light in an aqueous solution was examined for possible value-added food colorants. The thermal degradation reactions were carried out at pH 3.0 (50 mM glycine buffer) in 50% EtOH/H(2)O. Deoxyshikonin (t(1/2) = 14.6 h, 60 degrees C) and isobutylshikinin (t(1/2) = 19.3 h, 60 degrees C) are relatively less stable than other shikonin derivatives (t(1/2) = 40-50 h, 60 degrees C). Activation energies of thermal degradation of the isolated pigments were calculated. The activation energy of deoxyshikonin was the highest (12.5 kcal mol(-)(1)) and that of beta-hydroxyisovalerylshikonin was the lowest (1.71 kcal mol(-)(1)) value.

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Others

Other Targets

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52438-12-7

358.39

C20H22O6

>98% (HPLC)

In Vitro:?DMSO : 10 mg/mL (27.90 mM)

CC(C)C(=O)O[C@H](CC=C(C)C)C1=CC(=O)c2c(O)ccc(O)c2C1=O

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(-20℃)

With Ice Pack

≥ 2 years