
Isbufylline
CAS No. 90162-60-0
Isbufylline ( —— )
产品货号. M28920 CAS No. 90162-60-0
除支气管扩张活性外,异丁茶碱还可发挥显着的抗炎作用。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥3540 | 有现货 |
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10MG | ¥5233 | 有现货 |
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25MG | ¥7995 | 有现货 |
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50MG | ¥11178 | 有现货 |
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100MG | ¥15066 | 有现货 |
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500MG | ¥30132 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Isbufylline
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述除支气管扩张活性外,异丁茶碱还可发挥显着的抗炎作用。
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产品描述Isbufylline can exert significant anti-inflammatory actions, in addition to its bronchodilator activity.(In Vivo):At a dose (106 μmol/kg i.p.) providing complete protection against acetylcholine aerosol-induced dyspnea in the guinea pig, Isbufylline inhibited platelet-activating factor (PAF)- and antigen-induced eosinophil infiltration into bronchoalveolar lavage fluid 24 h after the challenge of normal and actively immunized guinea pigs, respectively. In addition, this dose of Isbufylline also inhibited capsaicin-induced extravasation of protein into bronchoalveolar lavage fluid. Isbufylline, 4.2 μmol/kg i.v., significantly inhibited PAF-induced bronchial hyper-responsiveness to i.v. histamine, without exerting evident bronchodilator activity. On the other hand, the bronchodilator, salbutamol, at a dose (10.4 μmol/kg i.p.) was shown to be equieffective to Isbufylline (106 μmol/kg i.p.) for blocking acetylcholine aerosol-induced dyspnea, had no protective action against PAF- or antigen-induced eosinophil recruitment in bronchoalveolar lavage fluid, or against capsaicin-induced plasma protein extravasation. Furthermore, salbutamol (3.5 μmol/kg) significantly potentiated allergen-induced cell infiltration and PAF-induced bronchial hyperresponsiveness.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number90162-60-0
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分子量236.275
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分子式C11H16N4O2
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(C)Cn1cnc2n(C)c(=O)n(C)c(=O)c12
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Morikawa T, et al. Ellagic acid glycosides with hepatoprotective activity from traditional Tibetan medicine Potentilla anserina. J Nat Med. 2018 Jan;72(1):317-325.
产品手册




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