Inh2-B1 ( STK1 inhibitor B1 )

产品货号. M15641 CAS No. 690216-38-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Inh2-B1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM.
产品描述

Inh2-B1 (STK1 inhibitor B1) is a novel specific S aureus Ser/Thr protein kinase (STK1) inhibitor with IC50 of 49 uM, directly binds to ATP-binding catalytic domain; exhibits in vitro growth inhibition of MRSA, and in vivo protection in mice against the lethal MRSA challenge; down-regulates cell wall hydrolase genes and disrupts the biofilm formation of MRSA.
同义词

STK1 inhibitor B1
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

——
适应症

——

CAS Number

690216-38-7
分子量

411.45
分子式

C19H13N3O4S2
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

Methyl 5-oxo-3-(phenyl carbamoyl)-1-thioxo-4,5dihydro[1,3]thiazolo[3,4-a]quinazoline-8-carboxylate

1. Kant S, et al. Sci Rep. 2017 Jul 11;7(1):5067.

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产品手册

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