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Infree
CAS No. 85801-02-1
Infree ( —— )
产品货号. M21168 CAS No. 85801-02-1
Infree 是吲哚美辛的前药。它作为非甾体抗炎药 (NSAID) 和缓解疾病抗风湿药 (DMARD)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥300 | 有现货 |
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| 10MG | ￥405 | 有现货 |
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| 25MG | ￥624 | 有现货 |
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| 50MG | ￥988 | 有现货 |
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| 100MG | ￥1482 | 有现货 |
|
| 200MG | ￥2228 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Infree
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Infree 是吲哚美辛的前药。它作为非甾体抗炎药 (NSAID) 和缓解疾病抗风湿药 (DMARD)。
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产品描述Infree is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).
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体外实验Indometacin farnesil (IMF) is a newly synthesized prodrug of indomethacin designed to reduce the occurrence of side-effects by esterification of the carboxyl group of indomethacin with farnesol. This modification is intended to decrease the extraction and subsequent rapid metabolism of the drug by the liver, so that lymphatic absorption would become a major route, and it was also anticipates that hydrolytic enzymes present in plasma and tissues, including inflamed tissue, would release indomethacin effectively from IMF.
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体内实验Indomethacin farnesil (IMF) can effectively release indomethacin when administered locally. Animal Model:Rats.Dosage:50 nmol a rat paw.Administration:Once.Result:Reduced the level of PGE2 in a dose dependent manner.
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同义词——
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通路Others
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靶点Other Targets
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受体others
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研究领域——
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适应症——
化学信息
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CAS Number85801-02-1
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分子量562.14
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分子式C34H40ClNO4
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纯度>98% (HPLC)
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溶解度——
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SMILESClc1ccc(cc1)C(=O)n3c2ccc(cc2c(CC(=O)OC\C=C(/C)CC\C=C(/C)CC\C=C(/C)C)c3C)OC
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化学全称3711-Trimethyldodeca-2610-trien-1-yl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ono K Hashimoto T Satoh T . Eosinophilic Pustular Folliculitis Clinically Presenting as Orofacial Granuloma: Successful Treatment with Indomethacin But Not Ibuprofen[J]. Acta Dermato Venereologica 2015 95(3):361-362.
