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Indican

CAS No. 487-60-5

Indican ( NSC-87517 | NSC 87517 | NSC87517 | Indoxyl-β-D-glucoside | 3-Indoxyl-beta-D-glucopyranoside )

产品货号. M27182 CAS No. 487-60-5

Indican 是一种天然保护化合物,用于保护肝脏。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥340 有现货
100MG ¥462 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Indican
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Indican 是一种天然保护化合物,用于保护肝脏。
  • 产品描述
    Indican is a natural protective compound that is used to protect the liver.(In Vitro):Oral single doses of Indican at 20, 40 mg/kg increase the systemic exposure of MTX and MRT by inhibiting multiple anion transporters including OAT 1, OAT 3, and MRP 4 via the major metabolite indoxyl sulfate (IS) .
  • 体外实验
    ——
  • 体内实验
    Indican ((Indoxyl-β-D-glucoside; oral; 20, 40 mg/kg; single dose) increases the systemic exposure and MRT of MTX through inhibition on multiple anion transporters including OAT 1, OAT 3 and MRP 4 by the major metabolite IS. Animal Model:Male Spraguee Dawley rats weighing 330-400 g Dosage:20, 40 mg/kg Administration:Orally Result:Increased the systemic exposure and multidrug resistance-associated protein (MRP) of Methotrexate (MTX; 5.0 mg/kg).
  • 同义词
    NSC-87517 | NSC 87517 | NSC87517 | Indoxyl-β-D-glucoside | 3-Indoxyl-beta-D-glucopyranoside
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    CCR2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    487-60-5
  • 分子量
    295.291
  • 分子式
    C14H17NO6
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 100 mg/mL (338.65 mM)
  • SMILES
    OC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Moree WJ, et al. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1869-73.
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