Indican
CAS No. 487-60-5
Indican ( NSC-87517 | NSC 87517 | NSC87517 | Indoxyl-β-D-glucoside | 3-Indoxyl-beta-D-glucopyranoside )
产品货号. M27182 CAS No. 487-60-5
Indican 是一种天然保护化合物,用于保护肝脏。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥340 | 有现货 |
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100MG | ¥462 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Indican
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Indican 是一种天然保护化合物,用于保护肝脏。
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产品描述Indican is a natural protective compound that is used to protect the liver.(In Vitro):Oral single doses of Indican at 20, 40 mg/kg increase the systemic exposure of MTX and MRT by inhibiting multiple anion transporters including OAT 1, OAT 3, and MRP 4 via the major metabolite indoxyl sulfate (IS) .
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体外实验——
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体内实验Indican ((Indoxyl-β-D-glucoside; oral; 20, 40 mg/kg; single dose) increases the systemic exposure and MRT of MTX through inhibition on multiple anion transporters including OAT 1, OAT 3 and MRP 4 by the major metabolite IS. Animal Model:Male Spraguee Dawley rats weighing 330-400 g Dosage:20, 40 mg/kg Administration:Orally Result:Increased the systemic exposure and multidrug resistance-associated protein (MRP) of Methotrexate (MTX; 5.0 mg/kg).
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同义词NSC-87517 | NSC 87517 | NSC87517 | Indoxyl-β-D-glucoside | 3-Indoxyl-beta-D-glucopyranoside
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通路Others
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靶点Other Targets
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受体CCR2
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研究领域——
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适应症——
化学信息
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CAS Number487-60-5
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分子量295.291
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分子式C14H17NO6
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (338.65 mM)
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SMILESOC[C@H]1O[C@@H](Oc2c[nH]c3ccccc23)[C@H](O)[C@@H](O)[C@@H]1O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Moree WJ, et al. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1869-73.
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