ISX-1

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

ISX-1 是一种异恶唑。 ISX-1 具有抗脂肪生成和促成骨活性。 ISX-1 可用于骨量减少和骨质疏松症的研究。

ISX-1 is an isoxazole. ISX-1 has anti-adipogenic and pro-osteogenic activities. ISX-1 can be used for the research of osteopenia and osteoporosis.

RT-PCRCell Line:Human bone marrow mesenchymal stem cells (hBMSCs)Concentration:0, 1.3, 6.5 and 33 μM Incubation Time:3 days Result:Inhibited the mRNA induction of PPARγ and FABP4 genes under the adipogenic differentiation of hBMSCs and showed no effect on C/EBPα expression.Western Blot Analysis Cell Line:HEK 293 cells Concentration:6.5 and 33 μM Incubation Time:6.5 and 33 μM Result:Increased both the amount of activated and total β-catenin.

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Others

Other Targets

Others

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909207-35-8

302.35

C14H14N4O2S

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : 50 mg/mL (165.37 mM; 超声助溶 )

C(NCCCN1C=CN=C1)(=O)C=2C=C(ON2)C3=CC=CS3

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(-20℃)

With Ice Pack

≥ 2 years