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INI-43

CAS No. 881046-01-1

INI-43 ( INI 43; INI43; INI-43 )

产品货号. M27884 CAS No. 881046-01-1

INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥721 有现货
10MG ¥1158 有现货
25MG ¥2341 有现货
50MG ¥3686 有现货
100MG ¥5443 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    INI-43
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
  • 产品描述
    INI-43, an inhibitor of Nuclear Import-43, shows a significant cytotoxic effect on various cervical and oesophageal cancer cell lines by targeting Kpnβ1 and interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NF.
  • 同义词
    INI 43; INI43; INI-43
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    PLD1;PLD2;Dopamine Receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    881046-01-1
  • 分子量
    385.5
  • 分子式
    C22H23N7
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CN(C)CCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc3ccccc3nc12
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Skafi N, et al. Phospholipase D: A new mediator during high phosphate-induced vascular calcification associated with chronic kidney disease. J Cell Physiol. 2019 Apr;234(4):4825-4839.
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