INCA-6
CAS No. 3519-82-2
INCA-6 ( Triptycene-1,4-quinone )
产品货号. M27468 CAS No. 3519-82-2
INCA-6 is an inhibitor of Nuclear factor of activated T cells (NFAT) and calcineurin-NFAT signaling.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥405 | 有现货 |
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10MG | ¥697 | 有现货 |
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25MG | ¥1393 | 有现货 |
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50MG | ¥2689 | 有现货 |
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100MG | ¥4585 | 有现货 |
|
500MG | ¥9963 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称INCA-6
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述INCA-6 is an inhibitor of Nuclear factor of activated T cells (NFAT) and calcineurin-NFAT signaling.
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产品描述INCA-6 is an inhibitor of Nuclear factor of activated T cells (NFAT) and calcineurin-NFAT signaling.(In Vitro):In human retinal microvascular endothelial cells, INCA-6 (1.0, 2.5 μM) significantly decreases VEGF and serum-induced proliferation without affecting baseline proliferation. In 3-Hz cells, INCA-6 (5 μM) prevents transient outward K+ current downregulation. INCA-6 (10 μM) significantly inhibits ATP-induced CXCL2 expression in rat primary microglia and BV-2 cells. INCA-6 (5 μM) protein expression and reduces SERCA2 transcript levels with and without thapsigargin.(In Vivo):INCA-6 (2.5, 5.0, and 25.0 μM; intravitreal) significantly reduces pathologic neovascularization in oxygen-induced retinopathy and decreases the severity of OIR in a dose dependent manner.
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同义词Triptycene-1,4-quinone
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通路Others
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靶点Other Targets
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受体prostaglandin F2α
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研究领域——
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适应症——
化学信息
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CAS Number3519-82-2
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分子量284.3
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分子式C20H12O2
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纯度>98% (HPLC)
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溶解度——
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SMILESO=C1C=CC(=O)C2=C1C3C=4C=CC=CC4C2C=5C=CC=CC53
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Baryla M, et al. Prostaglandin F(2α) stimulates adhesion, migration, invasion and proliferation of the human trophoblast cell line HTR-8/SVneo. Placenta. 2019 Feb;77:19-29.
产品手册
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