IMT1B
CAS No. 2304621-06-3
IMT1B ( 3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-; LDC203974 )
产品货号. M24045 CAS No. 2304621-06-3
IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2657 | 有现货 |
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10MG | ¥4560 | 有现货 |
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25MG | ¥7209 | 有现货 |
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50MG | ¥9963 | 有现货 |
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100MG | ¥13527 | 有现货 |
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500MG | ¥27135 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称IMT1B
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
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产品描述IMT1B is an orally active, noncompetitive and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT) and inhibits mitochondrial DNA (mtDNA) expression. It has anti-tumour effects.
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同义词3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-; LDC203974
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通路Others
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靶点Other Targets
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受体POLRMT
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研究领域——
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适应症——
化学信息
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CAS Number2304621-06-3
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分子量473.9
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分子式C24H21ClFNO6
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纯度>98% (HPLC)
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溶解度DMSO:250 mg/mL?(527.56 mM;?Need ultrasonic)
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SMILESC[C@H](C(=O)N1CCC[C@@H](C1)C(=O)O)OC2=CC3=C(C=C2)C(=CC(=O)O3)C4=C(C=C(C=C4)F)Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Nina A Bonekamp, et al. Small-molecule inhibitors of human mitochondrial DNA transcription. Nature. 2020 Dec;588(7839):712-716.
产品手册
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