IMP-1088 ( —— )

产品货号. M28622 CAS No. 2059148-82-0

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

IMP-1088
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.
产品描述

IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.(In Vitro):IMP-1088 (1-1000 nM) blocks production of infectious virus and inhibits single cycle replication in primary human bronchial epithelial cells (hBEC) infected with rhinovirus RV-A1 (MOI 5) for 7 h. IMP-1088 significantly inhibits production of infectious virus even when added up to 3 hours post-infection.IMP-1088 (500 nM) inhibits production of infectious rhinovirus particles by blocking virus assembly in HeLa cells infected with rhinovirus RV-A16 (MOI 20) for 6 h.
同义词

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通路

Others
靶点

Other Targets
受体

D4 Receptor
研究领域

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适应症

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1.Belliotti TR, et al. Isoindolinone enantiomers having affinity for the dopamine D4 receptor. Bioorg Med Chem Lett. 1998 Jun 16;8(12):1499-502.

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