
IMAB027
CAS No. 1650599-68-0
IMAB027 ( —— )
产品货号. M37166 CAS No. 1650599-68-0
IMAB027 (ASP1650) 是一种特异性抗 CLDN6 单克隆抗体,而 CLDN6 (Claudin 6) 是一种紧密连接膜蛋白,在各种人类癌症类型中异常表达,尤其是在卵巢癌中。IMAB 027 具有抗肿瘤活性,并诱导 CLDN6+ 卵巢癌和睾丸癌细胞凋亡。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥3850 | 有现货 |
![]() ![]() |
5MG | ¥5838 | 有现货 |
![]() ![]() |
10MG | ¥7873 | 有现货 |
![]() ![]() |
25MG | ¥11183 | 有现货 |
![]() ![]() |
50MG | ¥15249 | 有现货 |
![]() ![]() |
500MG | 获取报价 | 有现货 |
![]() ![]() |
1G | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称IMAB027
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述IMAB027 (ASP1650) 是一种特异性抗 CLDN6 单克隆抗体,而 CLDN6 (Claudin 6) 是一种紧密连接膜蛋白,在各种人类癌症类型中异常表达,尤其是在卵巢癌中。IMAB 027 具有抗肿瘤活性,并诱导 CLDN6+ 卵巢癌和睾丸癌细胞凋亡。
-
产品描述IMAB027 (ASP1650) is a specific anti-CLDN6 mAb, while CLDN6 (Claudin 6) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6+ ovarian and testicular cancer cell lines.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域——
-
适应症——
化学信息
-
CAS Number1650599-68-0
-
分子量
-
分子式——
-
纯度>98% (HPLC)
-
溶解度——
-
SMILES——
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Türeci ?, t al. The anti-claudin 6 antibody, IMAB027, induces antibody-dependent cellular and complement-dependent cytotoxicity in claudin 6-expressing cancer cells[J]. Cancer Research, 2018, 78(13_Supplement): 882-882.
产品手册




关联产品
-
Mespirenone
Mespirenone is a spironolactone derivative and aldosterone antagonist with diuretic effects.
-
pp60 c-src (521-533)...
Peptide corresponding to the pp60c-src carboxy terminal regulatory domain; phosphorylated at Tyr527. Binds to pp60c-src and pp60v-src at the SH2 domain, suppressing their tyrosine kinase activity and transforming potential.
-
Rhein-8-glucoside
Rhein-8-glucoside 具有低通便活性。