I-2906 ( I 2906;I2906 )

产品货号. M14114 CAS No. 331963-29-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

I-2906
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity.
产品描述

A novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity; shows good activity against M. tuberculosis H37Ra with MIC of 0.5 ug/ml; significantlt reduces bacterial loads of both lungs and spleen in a murine model.Bacterial Infection Preclinical
同义词

I 2906;I2906
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

Infection
适应症

Bacterial Infection

CAS Number

331963-29-2
分子量

443.58
分子式

C25H37N3O4
纯度

>98% (HPLC)
溶解度

10 mM in DMSO
SMILES

CCCCCCCCCCCCC(=O)NNC(=O)C1=C(C2=CC=CC=C2N(C1=O)CC)O
化学全称

3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, 2-(1-oxotridecyl)hydrazide

1. Lu J, et al. Pharmacology. 2010;85(6):365-71.

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