Hyperoside

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Hyperoside 是一种 NF-κB 抑制剂，从 Hypericum monogynum 中发现。Hyperoside 具有抗肿瘤、抗真菌、抗炎症、抗病毒和抗氧化的活性，并能诱导细胞凋亡。

Extracted from clusiaceaefruit;Suitability:Ethanol,methanol,acetone and pyridine;Store the product in sealed,cool and dry condition.

Cell Viability Assay Cell Line:MCF-7 and 4T1 cellsConcentration:12.5, 25, 50, 75, or 100 μM Incubation Time:6, 12, or 24 h Result:Inhibited cell growth in a time- and concentration-dependent manner.Apoptosis Analysis Cell Line:MCF-7 and 4T1 cells Concentration:25, 50 and 100 μM Incubation Time:24 h Result:Increased the expressions of Bax, cleaved caspase-3 and cleaved PARP, and decreased Bcl-2 in mRNA and protein levels.

Animal Model:Balb/c mice injected with 4T1 cells Dosage:50 mg/kg Administration:Intraperitoneal injection; 50 mg/kg; every two day for 18 days Result:Reduced the average tumor volume compared to the control group.Decreased Bcl-2 and increased bax and cleaved caspase-3.

Hyperoside | NSC 407304 | Quercetin-3-O-galactoside

Others

Other Targets

Others

Inflammation/Immunology

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482-36-0

464.38

C21H20O12

>98% (HPLC)

DMSO: 10 mM

C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)O)O)O

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(-20℃)

With Ice Pack

≥ 2 years