Hydroxybupropion

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Hydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent.

Hydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake (IC50: 1.7 μM). Hydroxybupropion is also a nACh receptor antagonist more potent than Bupropion.(In Vitro):Hydroxybupropion shows stronger antitetrabenazine activity and has a lower LD50 value than the erythro- and threo- metabolites. Hydroxybupropion inhibits norepinephrine and dopamine uptake, antagonizes nicotine, and shows antidepressant effects in rodents.

6-Hydroxybupropion; Hydroxybupropion, (+/-)-; Hydroxybupropione

Others

Other Targets

PEGs

——

——

92264-81-8

255.7

C13H18ClNO2

>98% (HPLC)

——

CC(NC(C)(C)CO)C(=O)c1cccc(Cl)c1

——

(-20℃)

With Ice Pack

≥ 2 years