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Hydroxybupropion
CAS No. 92264-81-8
Hydroxybupropion ( 6-Hydroxybupropion; Hydroxybupropion, (+/-)-; Hydroxybupropione )
产品货号. M26253 CAS No. 92264-81-8
Hydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1426 | 有现货 |
|
| 5MG | ￥2406 | 有现货 |
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| 10MG | ￥3750 | 有现货 |
|
| 25MG | ￥6018 | 有现货 |
|
| 50MG | ￥7995 | 有现货 |
|
| 100MG | ￥11097 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Hydroxybupropion
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Hydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent.
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产品描述Hydroxybupropion is the active metabolite of Bupropion metabolized by CYP2B6. Bupropion is an antidepressant and smoking-cessation agent. Hydroxybupropion inhibits norepinephrine uptake (IC50: 1.7 μM). Hydroxybupropion is also a nACh receptor antagonist more potent than Bupropion.(In Vitro):Hydroxybupropion shows stronger antitetrabenazine activity and has a lower LD50 value than the erythro- and threo- metabolites. Hydroxybupropion inhibits norepinephrine and dopamine uptake, antagonizes nicotine, and shows antidepressant effects in rodents.
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同义词6-Hydroxybupropion; Hydroxybupropion, (+/-)-; Hydroxybupropione
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通路Others
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靶点Other Targets
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受体PEGs
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研究领域——
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适应症——
化学信息
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CAS Number92264-81-8
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分子量255.7
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分子式C13H18ClNO2
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(NC(C)(C)CO)C(=O)c1cccc(Cl)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ohoka N, et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). J Biol Chem. 2017 Mar 17;292(11):4556-4570.
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