Herniarin ( 7-Methoxycoumarin | Methyl umbelliferyl ether )

产品货号. M18747 CAS No. 531-59-9

Herniarin 是一种天然香豆素，具有抗肿瘤作用。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
500MG	￥340	有现货
1G	获取报价	有现货

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生物学信息

产品名称

Herniarin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Herniarin 是一种天然香豆素，具有抗肿瘤作用。
产品描述

Herniarin is a natural coumarin with antitumor effect.(In Vitro):Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
体外实验

Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
体内实验

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同义词

7-Methoxycoumarin | Methyl umbelliferyl ether
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

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化学信息

CAS Number

531-59-9
分子量

176.17
分子式

C10H8O3
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 125 mg/mL; 709.54 mM
SMILES

COc1ccc2ccc(=O)oc2c1
化学全称

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运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.

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