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Herniarin

CAS No. 531-59-9

Herniarin ( 7-Methoxycoumarin | Methyl umbelliferyl ether )

产品货号. M18747 CAS No. 531-59-9

Herniarin 是一种天然香豆素,具有抗肿瘤作用。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥340 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Herniarin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Herniarin 是一种天然香豆素,具有抗肿瘤作用。
  • 产品描述
    Herniarin is a natural coumarin with antitumor effect.(In Vitro):Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
  • 体外实验
    Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
  • 体内实验
    ——
  • 同义词
    7-Methoxycoumarin | Methyl umbelliferyl ether
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    531-59-9
  • 分子量
    176.17
  • 分子式
    C10H8O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO : ≥ 125 mg/mL; 709.54 mM
  • SMILES
    COc1ccc2ccc(=O)oc2c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.
产品手册
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