021-51111890
购物车（）
sales@molnova.cn
Herniarin
CAS No. 531-59-9
Herniarin ( 7-Methoxycoumarin | Methyl umbelliferyl ether )
产品货号. M18747 CAS No. 531-59-9
Herniarin 是一种天然香豆素，具有抗肿瘤作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 500MG | ￥340 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Herniarin
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Herniarin 是一种天然香豆素，具有抗肿瘤作用。
-
产品描述Herniarin is a natural coumarin with antitumor effect.(In Vitro):Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
-
体外实验Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
-
体内实验——
-
同义词7-Methoxycoumarin | Methyl umbelliferyl ether
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域Others-Field
-
适应症——
化学信息
-
CAS Number531-59-9
-
分子量176.17
-
分子式C10H8O3
-
纯度>98% (HPLC)
-
溶解度DMSO : ≥ 125 mg/mL; 709.54 mM
-
SMILESCOc1ccc2ccc(=O)oc2c1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.
产品手册
关联产品
-
Latanoprostene bunod
Latanoprostene Bunod 是一氧化氮 (NO) 供给型前列腺素 F2a 类似物，是一种局部眼科治疗化合物。
-
Sodium D-lactate
乳酸是一种有机酸。它是一种手性分子，由两种光学异构体L-乳酸和D-乳酸组成，其中L-异构体在生物体中最常见。乳酸也是一种微生物代谢产物。
-
BOS-318
BOS-318 是一种 Furin 抑制剂，具有缓慢解离、高选择性和细胞渗透性的特点。
