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Hemin

CAS No. 16009-13-5

Hemin ( Hemin chloride )

产品货号. M12298 CAS No. 16009-13-5

Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
1G ¥340 有现货

生物学信息

  • 产品名称
    Hemin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type.
  • 产品描述
    Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type; increases the size of autophagic vacuoles and induces mitophagy in K562 cells; a heme oxygenase (HO)1 inducer.
  • 同义词
    Hemin chloride
  • 通路
    Autophagy
  • 靶点
    Autophagy
  • 受体
    Autophagy
  • 研究领域
    Cardiovascular Disease
  • 适应症
    ——

化学信息

  • CAS Number
    16009-13-5
  • 分子量
    651.94
  • 分子式
    C34H32ClFeN4O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 6.6 mg/mL
  • SMILES
    CC1=C(CCC(O)=O)/C2=C/C3=C(CCC(O)=O)C(C)=C(/C=C4C(C)=C(C=C)C(/C=C5C(C)=C(C=C)C(/C=C1\[N-]2)=N/5)=N/4)[N-]3.[Fe+3]
  • 化学全称
    Ferrate(2-), chloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, hydrogen (1:2), (SP-5-13)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Fader CM, et al. Biol Cell. 2016 Apr;108(4):77-95.
2. Higdon AN, et al. Am J Physiol Heart Circ Physiol. 2012 Apr 1;302(7):H1394-409.
产品手册
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