Harpagoside
CAS No. 19210-12-9
Harpagoside ( SMR001233395; Eharpagoside )
产品货号. M18178 CAS No. 19210-12-9
Harpagoside has anti-inflammatory activity at 3 mM concentration, shows moderate inhibition of seed germination.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥470 | 有现货 |
|
10MG | ¥737 | 有现货 |
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25MG | ¥1337 | 有现货 |
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50MG | ¥1993 | 有现货 |
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100MG | ¥3005 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Harpagoside
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Harpagoside has anti-inflammatory activity at 3 mM concentration, shows moderate inhibition of seed germination.
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产品描述Harpagoside is an anti-inflammatory small molecule natural product originally isolated from the Harpagophytum procumbens (Devil’s Claw) root, but can be isolated from other plants such as Crophularia ningpoensis Hemsl (Figwort). Treatment of HepG2 cells with Harpagoside demonstrated suppression of NF-κB nuclear translocation and degradation of IκB-α, blocking NF-κB activation. Multiple anti-inflammatory cellular effects were correlated with this blockade, as Harpagoside was observed to inhibit the expression of inflammation-mediating enzymes cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and to reduce lipopolysaccharide-induced mRNA levels. The suppression of NF-κB activation is indicated as the mechanism beneath the anti-inflammatory effects of Harpagoside.
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同义词SMR001233395; Eharpagoside
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通路Others
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靶点Other Targets
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number19210-12-9
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分子量494.49
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分子式C24H30O11
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纯度98%
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溶解度——
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SMILESCC1(CC(C2(C1C(OC=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)OC(=O)C=CC4=CC=CC=C4
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化学全称[(1S,4aS,5R,7S,7aS)-4a,5-dihydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,5,6,7a-tetrahydrocyclopenta[c]pyran-7-yl] (E)-3-phenylprop-2-enoate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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