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HQNO

CAS No. 341-88-8

HQNO ( —— )

产品货号. M22043 CAS No. 341-88-8

HQNO 是从铜绿假单胞菌中分离出来的天然产物,是电子传递链的有效抑制剂(复合物 III 的 Kd 为 64 nM)。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥405 有现货
10MG ¥648 有现货
25MG ¥1199 有现货
50MG ¥2130 有现货
100MG ¥3686 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    HQNO
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    HQNO 是从铜绿假单胞菌中分离出来的天然产物,是电子传递链的有效抑制剂(复合物 III 的 Kd 为 64 nM)。
  • 产品描述
    HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    mitochondrial NDH-2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    341-88-8
  • 分子量
    259.34
  • 分子式
    C16H21NO2
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 5 mg/mL (19.28 mM)
  • SMILES
    CCCCCCCC1=CC(=O)C2=CC=CC=C2N1O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Jessica Petri, et al. Structure of the NDH-2 - HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):482-490.2. Kang J , Kim Y J . HQNO-sensitive NADH:Quinone Oxidoreductase of Bacillus cereus KCTC 3674[J]. J Biochem Mol Biol, 2007, 40(1):53-57.
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