HDL376 ( HDL-376; HDL 376; SDZ HDL376; SDZ-HDL376; SDZHDL376 )

产品货号. M27769 CAS No. 147751-31-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

HDL376
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

HDL376 is a scavenger receptor BI inhibitor.
产品描述

HDL376 is a scavenger receptor BI inhibitor.(In Vivo):HDL376 was shown to raise HDL cholesterol in the rat (normal-fed 80 mg/kg/day), hamster (normal-fed 52 mg/kg/day, chow-fed 64 mg/kg/day), dog (normal-fed 35 mg/kg/day), rhesus monkey (12 mg/kg/day), and cynomolgus monkeymodels (12 mg/kg/day).
同义词

HDL-376; HDL 376; SDZ HDL376; SDZ-HDL376; SDZHDL376
通路

Others
靶点

Other Targets
受体

MCU
研究领域

——
适应症

——

1.Giulia Di Marco, et al. A High-Throughput Screening Identifies MICU1 Targeting Compounds. Cell Rep. 2020 Feb 18;30(7):2321-2331.e6.

计算器

产品手册

关联产品

Methyl nomilinate

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
ent-16beta,17-dihydr...

ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid is a natural product of Xanthium, Asteraceae. ent-16beta,17-dihydroxy-9(11)-kauren-19-oic acid can be used as a reference standard.
ML-180

ML-180 is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .ML-180 (0.5-5 μM; 24 hours) shows a significant inhibition of cyclin-D1 and cyclin-E1 expression in hepatic cells, but has little effect on repression in SK-OV-3 cells[2]. ML-180 (5 μM; 24 hours) leads to a rapid decrease of LRH-1 expression and efficiently represses endogenous LRH-1 signaling.