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H3B-120
CAS No. 2194903-42-7
H3B-120 ( —— )
产品货号. M26243 CAS No. 2194903-42-7
H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2001 | 有现货 |
|
| 10MG | ￥3345 | 有现货 |
|
| 25MG | ￥5605 | 有现货 |
|
| 50MG | ￥7979 | 有现货 |
|
| 100MG | ￥10773 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称H3B-120
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity.
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产品描述H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity.(In Vitro):H3B-120 (25, 50, 75, 100 μM) inhibits urea production in a dose-dependent manner, although the cellular potency decreases significantly compared with enzymatic assays.?The half-life of H3B-120 is only 40 min.?H3B-120 has no inhibition of CPS2 activity of CAD (CPS2, aspartyl transcarbamylase, dihydroorotase).
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同义词——
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通路Others
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靶点Other Targets
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受体Akt; p38 MAPK
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研究领域——
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适应症——
化学信息
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CAS Number2194903-42-7
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分子量372.5
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分子式C19H24N4O2S
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纯度>98% (HPLC)
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溶解度——
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SMILESCN(Cc1ccccc1)C(=O)N1CCC(CC1)C(=O)Nc1nc(C)cs1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.?Bai ZT,?et al. Inhibition of invasion by N-trans-feruloyloctopamine via AKT, p38MAPK and EMT related signals in hepatocellular carcinoma cells. Bioorg Med Chem Lett.?2017 Feb 15;27(4):989-993.
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