H-Val-Pro-Pro-OH

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

H-Val-Pro-Pro-OH 是血管紧张素 I 转换酶 (ACE) 的抑制剂 (IC50 : 9 μM)。

H-Val-Pro-Pro-OH is an inhibitor of Angiotensin I converting enzyme (ACE)( IC50 : 9 μM).

H-Val-Pro-Pro-OH, a proline peptides derivative, could inhibit Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. H-Val-Pro-Pro-OH could enhance insulin sensitivity and prevent insulin resistance in 3T3-F442A pre-adipocytes. H-Val-Pro-Pro-OH also has anti-hypertensive and anti-inflammatory functions. H-Val-Pro-Pro-OH further enhances the expression of glucose transporter 4 (GLUT4) in adipocytes and restores glucose uptake in TNF-treated adipocytes.

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Endocrinology/Hormones

RAAS

ACE

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58872-39-2

311.38

C15H25N3O4

>98% (HPLC)

In Vitro:?DMSO : 12.5 mg/mL (40.14 mM)

CC(C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(O)=O

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(-20℃)

With Ice Pack

≥ 2 years