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Guanadrel

CAS No. 40580-59-4

Guanadrel ( —— )

产品货号. M24365 CAS No. 40580-59-4

Guanadrel 是一种具有口服活性的螺旋酮类的节后肾上腺素能 (postganglionic adrenergic) 抑制剂,可用作抗高血压研究。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥4965 有现货
100MG ¥10838 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Guanadrel
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Guanadrel 是一种具有口服活性的螺旋酮类的节后肾上腺素能 (postganglionic adrenergic) 抑制剂,可用作抗高血压研究。
  • 产品描述
    Guanadrel is an antihypertensive agent.?
  • 体外实验
    ——
  • 体内实验
    Guanadrel (oral gavage, 15-400 mg/kg, every day, 6-52 weeks) has little toxicity to the nervous system in rats and dogs. Animal Model:Rats, dogs Dosage:15-400 mg/kg Administration:Oral gavage; every day; 6-52 weeks Result:Showed a slight increase in the weight of the prostate and adrenal glands while loss in the kidney in rats.Decreased weight gain values in a dose-dependent manner but liver function is normal in dogs.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    40580-59-4
  • 分子量
    213.28
  • 分子式
    C10H19N3O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?DMSO : 50 mg/mL (234.43 mM)
  • SMILES
    NC(=N)NCC1COC2(CCCCC2)O1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Ming X , Li X , Tang X , et al. N-Hydroxyl derivatives of guanidine based drugs as enzymatic NO donors[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 32(52):no-no.
产品手册
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