021-51111890
购物车（）
sales@molnova.cn
Gracillin
CAS No. 19083-00-2
Gracillin ( Gracillin | NSC-698787 | NSC 698787 | NSC698787 )
产品货号. M18168 CAS No. 19083-00-2
Gracillin 可诱导 HL60 细胞的细胞周期停滞、氧化应激和细胞凋亡，具有开发为抗肿瘤药物的潜力。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥494 | 有现货 |
|
| 5MG | ￥882 | 有现货 |
|
| 10MG | ￥1173 | 有现货 |
|
| 25MG | ￥2628 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Gracillin
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Gracillin 可诱导 HL60 细胞的细胞周期停滞、氧化应激和细胞凋亡，具有开发为抗肿瘤药物的潜力。
-
产品描述Gracillin is a steroidal saponin that has been found in C. speciosus and has diverse biological activities. Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1.
-
体外实验Apoptosis Analysis Cell Line:A549 cells Concentration:0-4 μM Incubation Time:24 h Result:Induced morphological changes.Apoptosis rate: 6.56%-67.43%.
-
体内实验——
-
同义词Gracillin | NSC-698787 | NSC 698787 | NSC698787
-
通路Others
-
靶点Other Targets
-
受体cell cycle arrest
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number19083-00-2
-
分子量885.05
-
分子式C45H72O17
-
纯度>98% (HPLC)
-
溶解度In Vitro:?DMSO : 100 mg/mL (112.99 mM)
-
SMILES[C@@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)O[C@@H]1CC2=CC[C@H]3[C@@H]4C[C@@H]5O[C@@]6([C@H]([C@@H]5[C@]4(CC[C@@H]3[C@]2(CC1)C)C)C)CC[C@H](CO6)C)CO)O
-
化学全称(2S,3R,4S,5R,6R)-2-(((2R,3R,4S,5R,6R)-3-hydroxy-2-(hydroxymethyl)-6-(((4S,5'R,6aR,6bS,8aR,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)-5-(((2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Chen CR,et al.Gracillin induces apoptosis in HL60 human leukemic cell line via oxidative stress and cell cycle arrest of G1.Pharmazie. 2015 Mar;70(3):199-204.
产品手册
关联产品
-
cis-Anethol
茴香脑是一种广泛存在于自然界的芳香化合物，广泛用作调味物质。
-
Peptide M
Peptide M is a synthetic Peptide, 50 aa, derived from streptococcus M protein, containing an additional c-terminal cysteine residue.
-
FliC, Serotype a (42...
This is amino acids 427 to 441 fragment belongs to the FliC, serotype a of the S. FliC epitope recognized by a CD4+ T cell from naturally infected C57BL/6 mice is located in a region common to a number of distinct Salmonella serovars such as the S. paratyphi.This dominant epitope is contained within the constant C-terminus of FliC.
