Glycitin ( Glycitein-7-beta-O-glucoside | Glycitin | ZX-AFC000687 )

产品货号. M18523 CAS No. 40246-10-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Glycitin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

黄豆黄素是从豆类中分离出来的天然异黄酮，可以促进骨髓基质细胞和成骨细胞的增殖，并抑制骨转换。
产品描述

Glycitin is a TAS2R agonist found in soy. It suppresses invasive activity of glioma cells, increases proliferation of mouse bone marrow stromal cells and osteoblasts, and inhibits adipocytic transdifferentiation of osteoblasts.
体外实验

Cell Viability Assay Cell Line:Bone marrow stem cells (BMSCs) Concentration:0.01, 0.5, 1, 5 and 10 μM Incubation Time:7 days Result:Increased cell proliferation and promoted osteoblast formation from BMSCs.
体内实验

Animal Model:BALB/c male mice (6-8 weeks old, 18-22 g weight) treated with LPS Dosage:5 mg/kg, 10 mg/kg and 20 mg/kg Administration:Intraperitoneal injection; three times (once every 8 h)Result:Obviously alleviated the lung injury induced by LPS.
同义词

Glycitein-7-beta-O-glucoside | Glycitin | ZX-AFC000687
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

40246-10-4
分子量

446.41
分子式

C22H22O10
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 38 mg/mL; 85.13 mM
SMILES

COc1c(cc2c(c1)c(=O)c(co2)c1ccc(cc1)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
化学全称

3-(4-hydroxyphenyl)-6-methoxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one