Gigantol ( —— )

产品货号. M18985 CAS No. 67884-30-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

Gigantol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells.
产品描述

Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows the protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway.Gigantol also shows α-glucosidase inhibitory activity.
同义词

——
通路

Others
靶点

Other Targets
受体

β-catenin; α-glucosidase
研究领域

Cancer
适应症

——

1. Yu S, et al. Bmc Complementary & Alternative Medicine, 2018, 18(1):59.

计算器

产品手册

关联产品

4'-Methoxyresveratro...

4'-Methoxyresveratrol is a natural product form the roots of Rheum palmatum Lhas significant hypoglycemic anti-inflammatory and antioxidant effects.
Chemerin-9 (149-157)...

Chemerin-9 (149-157) TFA, the nonapeptide (149)YFPGQFAFS(157) (chemerin-9), corresponding to the C terminus of processed chemerin, retains most of the activity of the full-size protein, with regard to agonism toward the chemerinR.
Secoisolariciresinol...

The heartwoods of Podocarpus spicata.