Genistin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

染料木苷是一种天然产物，常见于大豆和豆制品中。

Genistin is a selective estrogen receptor modulator (SERM) found in soy. It is the less active glycoside analog of genistein. It acts as a phytoestrogen, induces cell cycle arrest and apoptosis in ovarian cancer cells, improves bone density and strength, and decreases myosin light chain kinase levels.

Genistin causes negative regulation of ERα. Genistin also effectively down-modulates ER nuclear translocation as well DNA binding activity in breast cancer cells. Moreover, GS effectively induced apoptosis and suppressed levels of oncogenic markers in MCF-7 cells.

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Genistein glucoside | CS-4240 | NSC5112 | NSC-5112 | Genistin

Membrane Transporter/Ion Channel

TRP/TRPV Channel

Others

Others-Field

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529-59-9

432.37

C21H20O10

>98% (HPLC)

DMSO : ≥ 43 mg/mL; 99.45 mM

c1cc(ccc1c1coc2cc(cc(c2c1=O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)O

5-hydroxy-3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

(-20℃)

With Ice Pack

≥ 2 years