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Garetosmab
CAS No. 2097125-54-5
Garetosmab ( —— )
产品货号. M36797 CAS No. 2097125-54-5
Garetosmab (REGN 2477) 是一种全人 IgG4 单克隆抗体，可特异性抑制激活素 A (activin A)。Garetosmab 可用于进行性骨化性纤维发育不良 (FOP) 的研究。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥4238 | 有现货 |
|
| 5MG | ￥6969 | 有现货 |
|
| 10MG | ￥11063 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Garetosmab
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Garetosmab (REGN 2477) 是一种全人 IgG4 单克隆抗体，可特异性抑制激活素 A (activin A)。Garetosmab 可用于进行性骨化性纤维发育不良 (FOP) 的研究。
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产品描述Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research.
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体外实验Garetosmab (REGN 2477) specifically binds to and blocks signaling of activin proteins containing the inhibin βα subunit (activins A, AB, and AC). In vitro, Garetosmab has high affinity and specificity for activins A, AB, and AC, but does not bind or functionally inhibit other TGF-β family ligands that share the same activin receptor pathways, including activin B, inhibin A, BMP-2, BMP6, BMP9, BMP10, GDF8, and GDF11.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体TGF-beta/Smad
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研究领域——
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适应症——
化学信息
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CAS Number2097125-54-5
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Frédéric Vanhoutte, et al. Pharmacokinetics and Pharmacodynamics of Garetosmab (Anti-Activin A): Results From a First-in-Human Phase 1 Study. J Clin Pharmacol. 2020 Nov;60(11):1424-1431.?
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