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Gamma-Methylleucine

CAS No. 57224-50-7

Gamma-Methylleucine ( gamma-Methyl-L-leucine; L-Neopentylglycine; 2-Amino-3-tert-butylpropionic acid )

产品货号. M27985 CAS No. 57224-50-7

Gamma-Methylleucine is an auxiliary for copper-catalyzed asymmetric Michael reactions.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥421 有现货
100MG ¥640 有现货
200MG ¥956 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Gamma-Methylleucine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Gamma-Methylleucine is an auxiliary for copper-catalyzed asymmetric Michael reactions.
  • 产品描述
    Gamma-Methylleucine is an auxiliary for copper-catalyzed asymmetric Michael reactions.(In Vivo):gamma-Methylleucine improved the binding affinity of the peptide for Y2R but also increased its anorectic activity in lean mice . Gamma-methylleucine resulted in loss of or significantly decreased the biological activity of ET-1, while high affinity for the ETA (IC50 = 0.42-0.70 nM) and ETB (IC50 = 0.17-0.43 nM) receptor was retained . Gamma-methylleucine was shown to have high antagonist activitiesin Sarafotoxin S6c-induced vasoconstriction of rabbit pulmonary artery (ET-1: pA2 8.4) and have the desirable characteristic of possessing no agonist activity at either receptor subtype .
  • 同义词
    gamma-Methyl-L-leucine; L-Neopentylglycine; 2-Amino-3-tert-butylpropionic acid
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    57224-50-7
  • 分子量
    145.2
  • 分子式
    C7H15NO2
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(C)(C)C[C@H](N)C(O)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Son MJ, et al. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming. Exp Mol Med. 2018 Dec 6;50(12):160.
产品手册
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