GW280264X ( Carbamic acid )

产品货号. M24871 CAS No. 866924-39-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

GW280264X
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

GW280264X 是 ADAM17 的抑制剂。
产品描述

GW280264X is an inhibitor of ADAM17 .
体外实验

Cell Viability Assay Cell Line:Glioblastoma-initiating cells (GIC) GS-7 cells Concentration:0.1, 1, and 3 μM Incubation Time:48 hours Result:Proliferation of GIC is inhibited through inhibition of ADAM10 and ADAM17.
体内实验

Animal Model:C57BL/6 miceDosage:100 ?μg/kg Administration:I.p. injected; every day for one week starting 4?h post-surgery Result:Showed significantly improved functional recovery compared to the control group.
同义词

Carbamic acid
通路

Others
靶点

Other Targets
受体

ADAM17
研究领域

——
适应症

——

CAS Number

866924-39-2
分子量

575.72
分子式

C28H41N5O6S
纯度

>98% (HPLC)
溶解度

DMSO:10 mM
SMILES

CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(=O)OCC1=CC=CC=C1)C(=O)NC2=NC=CS2)N(C=O)O
化学全称

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