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GW0742
CAS No. 317318-84-6
GW0742 ( GW0742; GW-0742; GW 0742; GW0742X )
产品货号. M17477 CAS No. 317318-84-6
GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥348 | 有现货 |
|
| 10MG | ￥551 | 有现货 |
|
| 25MG | ￥1029 | 有现货 |
|
| 50MG | ￥1871 | 有现货 |
|
| 100MG | ￥3248 | 有现货 |
|
| 500MG | ￥7719 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GW0742
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).
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产品描述GW0742, also known as GW610742 and GW0742X is a PPARδ/β agonist. GW0742 Induces Early Neuronal Maturation of Cortical Post-Mitotic Neurons. GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity. GW0742 has direct protective effects on right heart hypertrophy.GW0742 may enhance lipid metabolism in heart both in vivo and in vitro.
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同义词GW0742; GW-0742; GW 0742; GW0742X
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通路Others
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靶点Other Targets
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受体PPARδ;PPARα;PPARγ
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研究领域Metabolic Disease
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适应症——
化学信息
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CAS Number317318-84-6
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分子量471.49
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分子式C21H17F4NO3S2
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纯度98%
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溶解度DMSO : ≥ 34 mg/mL; 72.11 mM
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SMILESCc1c(CSc2ccc(OCC(=O)O)c(C)c2)sc(n1)c1ccc(c(F)c1)C(F)(F)F
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化学全称[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methyl phenoxy]-acetic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Galuppo M, et al. GW0742, a high affinity PPAR-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice. Int J Immunopathol Pharmacol. 2010 Oct-Dec;23(4):1033-46.
产品手册
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