GW0742

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).

GW0742, also known as GW610742 and GW0742X is a PPARδ/β agonist. GW0742 Induces Early Neuronal Maturation of Cortical Post-Mitotic Neurons. GW0742 prevents hypertension, vascular inflammatory and oxidative status, and endothelial dysfunction in diet-induced obesity. GW0742 has direct protective effects on right heart hypertrophy.GW0742 may enhance lipid metabolism in heart both in vivo and in vitro.

GW0742; GW-0742; GW 0742; GW0742X

Others

Other Targets

PPARδ;PPARα;PPARγ

Metabolic Disease

——

317318-84-6

471.49

C21H17F4NO3S2

98%

DMSO : ≥ 34 mg/mL; 72.11 mM

Cc1c(CSc2ccc(OCC(=O)O)c(C)c2)sc(n1)c1ccc(c(F)c1)C(F)(F)F

[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methyl phenoxy]-acetic acid

(-20℃)

With Ice Pack

≥ 2 years