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GSK-2140944
CAS No. 1075236-89-3
GSK-2140944 ( Gepotidacin;GSK2140944 )
产品货号. M10308 CAS No. 1075236-89-3
GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥2948 | 有现货 |
|
| 50MG | ￥15714 | 有现货 |
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| 100MG | ￥22518 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GSK-2140944
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens.
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产品描述GSK-2140944 (Gepotidacin) is a novel potent, selective bacterial type II topoisomerase inhibitor in development for the treatment of conventional and biothreat pathogens, including Gram-positive pathogens and MRSA; shows antibacterial activity against MSSA and MRSA isolates (MIC90=0.5 ug/ml).Bacterial Infection Phase 2 Clinical
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同义词Gepotidacin;GSK2140944
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域Infection
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适应症Bacterial Infection
化学信息
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CAS Number1075236-89-3
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分子量448.53
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分子式C24H28N6O3
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纯度>98% (HPLC)
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溶解度DMSO : 7.14 mg/mL 15.92 mM
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SMILESO=C(C=NC(C=C1)=C23)N3[C@H](CN4CCC(NCC(N=C5)=CC6=C5OCCC6)CC4)CN2C1=O
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化学全称(2R)-2-[[4-[[(3,4-Dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl]amino]-1-piperidinyl]methyl]-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Bax BD, et al. Nature. 2010 Aug 19;466(7309):935-40.
2. Biedenbach DJ, et al. Antimicrob Agents Chemother. 2016 Jan 4;60(3):1918-23.
3. So W, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4956-61.
4. Farrell DJ, et al. Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02047-16.
2. Biedenbach DJ, et al. Antimicrob Agents Chemother. 2016 Jan 4;60(3):1918-23.
3. So W, et al. Antimicrob Agents Chemother. 2015 Aug;59(8):4956-61.
4. Farrell DJ, et al. Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e02047-16.
产品手册
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