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GS-143

CAS No. 916232-21-8

GS-143 ( GS 143; GS143 )

产品货号. M24964 CAS No. 916232-21-8

GS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥437 有现货
5MG ¥721 有现货
10MG ¥1134 有现货
25MG ¥2333 有现货
50MG ¥3686 有现货
100MG ¥5484 有现货
500MG ¥11583 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    GS-143
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    GS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation.
  • 产品描述
    GS143 is a selec-tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup-presses NF-κB acti-va-tion and tran-scrip-tion of tar-get genes and does not inhibit proteasome activity. GS143 has anti-asthma effect
  • 同义词
    GS 143; GS143
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    IκBα?phosphorylation
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    916232-21-8
  • 分子量
    466.5
  • 分子式
    C28H19FN2O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:40 mg/mL?(85.75 mM;?Need ultrasonic)
  • SMILES
    OC(c(cc1)ccc1N(C1=O)N=C(Cc2ccccc2)C1=Cc1ccc(-c(cccc2)c2F)o1)=O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Rashmi BS, Gayathri D. Molecular characterization of gluten hydrolysing Bacillus sp. and their efficacy and biotherapeutic potential as probiotics using Caco-2 cell line. J Appl Microbiol. 2017 Sep;123(3):759-772. doi: 10.1111/jam.13517. Epub 2017 Aug 4. PubMed PMID: 28637081.
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