021-51111890
购物车（）
sales@molnova.cn
GRP-60367
CAS No. 1309241-34-6
GRP-60367 ( —— )
产品货号. M22631 CAS No. 1309241-34-6
GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1604 | 有现货 |
|
| 5MG | ￥2406 | 有现货 |
|
| 10MG | ￥3669 | 有现货 |
|
| 25MG | ￥6051 | 有现货 |
|
| 50MG | ￥8505 | 有现货 |
|
| 100MG | ￥11502 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称GRP-60367
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
-
产品描述GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体RABV
-
研究领域——
-
适应症——
化学信息
-
CAS Number1309241-34-6
-
分子量353.46
-
分子式C21H27N3O2
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCc1ccc(C)c(OCCNC2CCN(CC2)C(=O)c2ccncc2)c1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Pont V D , Wirblich C , Yoon J J , et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor[J]. Journal of Virology, 2020, 94(13).
产品手册
关联产品
-
CAY10781
CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
-
CLOZAPINE N-OXIDE
Clozapine N-oxide is a major metabolite of clozapine that can be detected in the earliest excretion time interval after clozapine administration.
-
Cephalosporin C zinc...
Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.?
