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GPNA hydrochloride
CAS No. 67953-08-6
GPNA hydrochloride ( —— )
产品货号. M22681 CAS No. 67953-08-6
GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥348 | 有现货 |
|
| 25MG | ￥632 | 有现货 |
|
| 50MG | ￥1077 | 有现货 |
|
| 100MG | ￥1482 | 有现货 |
|
| 500MG | ￥3718 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GPNA hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT).
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产品描述GPNA hydrochloride is specific glutamine (Gln) transporter ASCT2(SLC1A5) inhibitor. GPNA reversibly induces apoptosis in A549 cells. GPNA hydrochloride is a well-known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride also inhibits Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2.GPNA (10-1000 μM; 48?hours) induces a dose-dependent to reduce of cell viability in A549 cells.
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同义词——
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通路Others
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靶点Other Targets
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受体ASCT2
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研究领域——
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适应症——
化学信息
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CAS Number67953-08-6
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分子量303.7
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分子式C11H14ClN3O5
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纯度>98% (HPLC)
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溶解度DMSO:124 mg/mL(408.3 mM)
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SMILESCl.N[C@@H](CCC(=O)Nc1ccc(cc1)[N+]([O-])=O)C(O)=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Corti A, et al. γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity. Sci Rep. 2019 Jan 29;9(1):891.
产品手册
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