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GNF4877
CAS No. 2041073-22-5
GNF4877 ( —— )
产品货号. M23913 CAS No. 2041073-22-5
GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6?nM and 16?nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥4682 | 有现货 |
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| 10MG | ￥7395 | 有现货 |
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| 25MG | ￥14013 | 有现货 |
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| 50MG | ￥24057 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GNF4877
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6?nM and 16?nM).
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产品描述GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6?nM and 16?nM). It?leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.
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同义词——
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通路Others
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靶点Other Targets
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受体GSK3β;DYRK1A
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研究领域——
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适应症——
化学信息
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CAS Number2041073-22-5
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分子量494.5
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分子式C25H27FN6O4
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纯度>98% (HPLC)
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溶解度DMSO:4.17 mg/mL (8.43 mM; Need ultrasonic and warming)
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SMILESCC(C)OC1=CC(=C(C=C1)F)C2=CN=C(C(=N2)C(=O)NC3=C(C=CN=C3)N4CCC[C@H](C4)C(=O)O)N
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Shen W, et al. Inhibition of DYRK1A and GSK3β induces human β-cell proliferation. Nat Commun. 2015 Oct 26;6:8372.
产品手册
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