021-51111890
购物车（）
sales@molnova.cn
GNF4877
CAS No. 2041073-22-5
GNF4877 ( —— )
产品货号. M23913 CAS No. 2041073-22-5
GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6?nM and 16?nM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥4682 | 有现货 |
|
| 10MG | ￥7395 | 有现货 |
|
| 25MG | ￥14013 | 有现货 |
|
| 50MG | ￥24057 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称GNF4877
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6?nM and 16?nM).
-
产品描述GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6?nM and 16?nM). It?leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体GSK3β;DYRK1A
-
研究领域——
-
适应症——
化学信息
-
CAS Number2041073-22-5
-
分子量494.5
-
分子式C25H27FN6O4
-
纯度>98% (HPLC)
-
溶解度DMSO:4.17 mg/mL (8.43 mM; Need ultrasonic and warming)
-
SMILESCC(C)OC1=CC(=C(C=C1)F)C2=CN=C(C(=N2)C(=O)NC3=C(C=CN=C3)N4CCC[C@H](C4)C(=O)O)N
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Shen W, et al. Inhibition of DYRK1A and GSK3β induces human β-cell proliferation. Nat Commun. 2015 Oct 26;6:8372.
产品手册
关联产品
-
Emodin anthrone
Emodin anthrone is a natural product belongs to the class of organic compounds known as anthracenes.?
-
5-amino-2-(2,6-dioxo...
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a E3 ligase ligand used in PROTAC technology.
-
NPB
NPB is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)
